Dr. Dy’s laboratory has two main lines of investigation:

Dy operatingDr. Dy operating with Prof. Elisabet Hagert during a visiting fellowship to her clinic in Stockholm, Sweden.1. Improving the delivery of care for patients with brachial plexus injury: 

  • Opportunities for secondary prevention to reduce trauma recidivism
    i. Collaborators: Margaret Olsen, PhD MPH; Timothy McBride PhD
    ii. Funding: Envolve Center for Health Behavior Change
  • A population-based assessment of mental health conditions in patients with brachial plexus injuries
    i. Collaborators: Margaret Olsen, PhD MPH; Timothy McBride PhD
    ii. Funding: Washington University Institute of Clinical and Translational Sciences
  • Demonstrating the economic value of brachial plexus injury reconstruction
    i. Collaborators: Margaret Olsen, PhD MPH; David Brogan, MD MSc; Wilson Z. Ray, MD
    ii. Funding: Washington University Center for Health Economics and Policy
  • Assessing coping strategies and social support networks in patients with brachial plexus injuries
    i. Collaborators: David Brogan, MD MSc; Wilson Z. Ray, MD
  • Examining barriers in deliver of care for patients with brachial plexus injury
    i. Collaborators: Aimee James, PhD; Scott Wolfe, MD; David Brogan, MD MSc; Wilson Z. Ray, MD

2. Identifying opportunities for improvement in delivery of orthopedic care for Medicaid patients:

  • Population-based exploration of disparities in access to orthopedic surgery
    i. Collaborators: Margaret Olsen, PhD MPH; Derek Brown PhD
    ii. Funding: Washington University Institute of Clinical and Translational Sciences KL2 Career Development Award
  • Utilization of common orthopaedic procedures in states with and without Medicaid expansion under the Affordable Care Act
    i. Collaborators: Margaret Olsen, PhD MPH; Derek Brown PhD
    ii. Funding: Oak Ridge Associated Universities Ralph E. Powe Junior Faculty Enhancement Award; Washington University Institute of Clinical and Translational Sciences Pilot Grant

 Dr. Brogan’s laboratory has three main lines of investigation: 

Brogan operating roomDr. Brogan, left, in the operating room.1. Evaluating techniques for and improving nerve repair and regeneration: 

  • In vivo Analysis of a Bioactive 3D Printed Peripheral Nerve Conduit
    i. Collaborators: Bret Ulery, PhD; Sheila Grant, PhD; Ferris Pfeiffer, PhD
    ii. Funding: University of Missouri Orthopaedic Association Seed Grant
  • Novel Immunomodulatory Peptide Polymers for VCA Rejection Prevention 
    i. Collaborators: Bret Ulery, PhD; Sheila Grant, PhD; Ferris Pfeiffer, PhD
    ii. Funding: DOD RTRP Concept Award RT160149  – Awarded June 2017
  • Optimizing outcomes of peripheral nerve defect repairs: a comparison of primary repair, biologic splinting, and intercalary allograft in a rat model
    i. Collaborators: Susan Mackinnon
    ii. Funding: KL2 Career Development Award – University of Missouri / Washington University

2. Nerve Imaging: 

  • This is an area of new interest for our lab.  We hope to utilize near-infrared fluorophores in collaboration with Dr. Achilefu in the Optical Imaging Laboratory to better assess nerve health intra-operatively.

3. Biomechanical Testing to Maximize Hand and Wrist Reconstruction:

  • Open vs Trans-osseous TFCC Tear Repair with DRUJ Instability: A Biomechanical Study
    i. Collaborators: Jayson Johnson, MD; Ferris Pfeiffer, PhD; Jill Jouret, MSc.
    ii. Funding: University of Missouri Orthopaedic Association Grant
  • Biomechanical Analysis of Capsular Repair versus Arthrex TFCC Ulnar Tunnel Repair for Triangular Fibrocartilage Complex Tears
    i. Collaborators: Jayson Johnson, MD; Ferris Pfeiffer, PhD; Jill Jouret, MSc.
    ii. Funding: University of Missouri Orthopaedic Association Grant
  • Locking Cap Fracture Fixation System
    i. Development of a novel fracture fixation system 
  • Automated Non-Contact Measurement of Hand Range of Motion
    i. Development of a system utilizing a 3D camera to automatically measure finger range of motion